On December 5th, 2017, Tell Every Amazing Lady® attended the Tannenbaum Helpern Syracuse & Hirschtritt’s Women’s Initiative Event at the Roger Smith Hotel in NYC. During this event, T.E.A.L.® was able to spread awareness about ovarian cancer while exploring products from featured women-owned businesses. It was a pleasure being able to connect with women entrepreneurs and professionals from all over New York. A huge thank you to Tannenbaum Helpern Syracuse & Hirschtritt, for inviting us to this inspiring event!
On Sunday, December 3rd, 2017, T.E.A.L.® participated in St. Joseph the Worker Catholic Academy Holiday fair to sell some merchandise and spread awareness information to the Windsor Terrace Community. About 300 people were in attendance and full of holiday spirit, including Santa!
Special thanks to St. Joseph the Worker Catholic Academy for inviting us to participate to promote awareness about ovarian cancer. We had a wonderful time collaborating with you and can’t wait for future collaboration projects!
On December 1st, 2017, T.E.A.L.® attended the 2017 NonProfit Excellence Awards at the CUNY Graduate Center. Thank you to the Nonprofit Coordinating Committee for hosting this event and congratulations to the winners, Children’s Aid Society, Brooklyn Community Services, and Gay Men’s Health Crisis!
On November 28th, 2017, T.E.A.L.® hosted a Holiday Open House to celebrate Giving Tuesday with our doors open to the public to stop by and visit along with survivors, volunteers, and staff. There were raffles, giveaways, trivia games and crafts.Thank you everyone for your generosity and support on Giving Tuesday. Big thank you to Lenny’s Pizzeria and Mimi’s Hummus for supplying snacks and food for the Open House. If you have not yet donated and would like to, please visit our Newman's Own Crowdrise to donate or join our team- fundraising is open until January 3rd, 2018!
T.E.A.L.® was honored to be a guest at the Marine Park Civic Association board meeting on November 21st, 2017. The meeting updated community leaders on what is going on in the area, and what to expect coming up in 2018. As an organization that had its start in Marine Park, with both of T.E.A.L.®’s co-founders Louisa and Pamela growing up in the neighborhood, it was a great opportunity to return to the place where it all started. T.E.A.L.® CEO Pamela Esposito-Amery gave a presentation about the work that T.E.A.L.® does throughout Brooklyn and beyond, focusing on the importance of family history and genetics and how it can sometimes play a role in the early detection of ovarian cancer.
T.E.A.L® was at the finish line volunteering and cheering for the amazing runners at this past weekend’s 4th annual NYCRUNS Queens Half Marathon on Saturday, November 18th, 2017. T.E.A.L.® was busy all week handing out educational materials to the thousands of runners at packet pickup while spreading cheer at the finish line on the day of the event. Thank you NYCRuns for including us in the event!
T.E.A.L® was invited to present at Wyckoff Hospital in Brooklyn, NY on November 21st, 2017. T.E.A.L® CEO Pamela Esposito-Amery and Programs Associate Melissa Belasoto spoke about the signs, symptoms, and risk factors of ovarian cancer to women’s health program leaders and general affiliates of Wyckoff Hospital. It was a great day of engaging Bushwick residents, and connecting with organizations and programs that help citizens throughout New York City. Thank you Wyckoff Hospital for including us and allowing us to share valuable information about ovarian cancer!
As part of T.E.A.L.®'s 2017 Medical Research Program, researchers at Johns Hopkins Medical Institutions (Co-PIs Dr. Tian-Li Wang, Dr. Tom Pisanic, and Dr. Amanda Nickles Fader) were awarded $10,000 towards their project Developing a microfluidic DNA methylation assessment platform for early noninvasive detection of ovarian cancer. This project is working to identify tumor-specific alterations in early precursor lesions of ovarian cancer and to exploit these alterations as biomarkers to detect ovarian cancers at early and low-volume stages.
Below you can find a press release from the researchers at Johns Hopkins Medical Institutions.
Methylomic analysis identifies tumor-specific alterations in early precursor lesions of ovarian cancer.
The goal of our study is to discover epigenetic alterations present in early precursor lesions of ovarian cancers and to exploit these alterations as biomarkers for early detection of this disease. Considerable effort has been made towards developing tests of protein and genetic biomarkers, including CA-125 and TP53 mutations, for early detection, but these approaches have yet to demonstrate sufficiently robust performance to warrant recommendations for use in general screening. We rationalize that epigenomic alterations which lead to gene silencing can occur during or even prior to the development of precursor lesions. We will therefore use these epigenetic markers to refine current genetics-based cancer detection tools. Our hope is that by combining genetic and epigenetic markers, we will be able to develop a detection modality with greatly enhanced sensitivity and specificity. Toward this goal, we assembled a multidisciplinary team at Johns Hopkins consisting of investigators, Dr. Thomas Pisanic (biomedical engineering), Dr. Amanda Fader (gynecology and oncology), and Dr. Tian-Li Wang (cancer genetics).
As part of T.E.A.L.®'s 2017 Medical Research Program, T.E.A.L.® awarded OCRFA $20,000 to fund research by Dr. Venkatesh Krishnan of Stanford University. This project, called Role of CCL15/CCR1 Axis in Ovarian Cancer Colonization of Omentum, will be investigating how the omental microenvironment contributes to the development of high-grade serous carcinoma (HGSC). The research team will be developing strategic therapeutic interventions that target precursor lesions and the microenvironment.